Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529458 | 0.90 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTHTTNPSR1 | |
| SCHEMBL528787 | 0.90 | MAPT (0.56) | ALDH1A1L3MBTL1MAPTHTTNPSR1 | |
| SCHEMBL528261 | 0.90 | MAPK1 (0.58) | ALDH1A1KCNK3KCNK9L3MBTL1MAPT | |
| SCHEMBL529092 | 0.87 | KMT2A (0.59) | ALDH1A1KCNK3KCNK9MAPTHTT | |
| SCHEMBL529422 | 0.86 | NPC1 (0.53) | ALDH1A1KCNK3KCNK9L3MBTL1MAPT | |
| SCHEMBL529523 | 0.86 | MAPT (0.56) | ALDH1A1KCNK3KCNK9L3MBTL1MAPT | |
| SCHEMBL529102 | 0.84 | MAPT (0.55) | ALDH1A1MAPTNPSR1KDM4EMEN1 | |
| SCHEMBL528145 | 0.83 | MAPT (0.55) | ALDH1A1L3MBTL1MAPTHTTNPSR1 | |
| SCHEMBL528847 | 0.83 | MEN1 (0.55) | ALDH1A1KCNK3KCNK9L3MBTL1MAPT | |
| SCHEMBL528522 | 0.82 | MEN1 (0.52) | ALDH1A1L3MBTL1MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |