Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529284 | 0.91 | ALDH1A1 (0.56) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL528265 | 0.91 | ALDH1A1 (0.54) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL528787 | 0.88 | MAPT (0.56) | MAPTKDM4EHPGDALDH1A1HTT | |
| SCHEMBL528937 | 0.88 | MAPT (0.47) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL528901 | 0.88 | MAPT (0.74) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL529518 | 0.86 | MAPT (0.46) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL529032 | 0.86 | MAPT (0.77) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL528487 | 0.85 | MAPT (0.46) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL528272 | 0.84 | MAPT (0.45) | MAPTLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL528702 | 0.84 | MAPT (0.58) | MAPTLMNAKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |