Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528290 | 0.92 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528484 | 0.89 | MEN1 (0.48) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL529730 | 0.89 | MAPT (0.58) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528646 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528817 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528386 | 0.85 | MAPT (0.53) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528754 | 0.84 | MAPT (0.56) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL529590 | 0.84 | LMNA (0.49) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528200 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL528292 | 0.82 | TP53 (0.46) | ALDH1A1MAPTHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |