Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528626 | 0.93 | ALDH1A1 (0.46) | MAPTLMNAALDH1A1HTTGAA | |
| SCHEMBL527888 | 0.89 | MAPT (0.45) | TP53MAPTLMNAALDH1A1HTT | |
| SCHEMBL529397 | 0.88 | MAPT (0.57) | TP53MAPTLMNAALDH1A1HTT | |
| SCHEMBL529297 | 0.87 | MAPT (0.59) | TP53MAPTLMNAALDH1A1HTT | |
| SCHEMBL528511 | 0.86 | KMT2A (0.52) | MAPTLMNAALDH1A1HTTNPSR1 | |
| SCHEMBL528672 | 0.84 | SMO (0.46) | TP53MAPTALDH1A1POLBGPR27 | |
| SCHEMBL529590 | 0.84 | LMNA (0.49) | MAPTLMNAALDH1A1HTTGAA | |
| SCHEMBL528985 | 0.84 | MAPT (0.54) | TP53MAPTLMNAALDH1A1HTT | |
| SCHEMBL527889 | 0.84 | ALDH1A1 (0.58) | TP53MAPTLMNAALDH1A1HTT | |
| SCHEMBL528111 | 0.83 | MAPT (0.48) | TP53MAPTLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |