SCHEMBL5288739

SCHEMBL5288739

C=C(CC(N)=O)C(=O)NCCCC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.44
ACHE P22303 7/20 0.41
MMP2 P08253 1/20 0.41
DPP7 Q9UHL4 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
ALOX15 P16050 1/20 0.39
EPHX2 P34913 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
PLA2G2A P14555 1/20 0.39
PLA2G4A P47712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5282297 0.88 MMP1 (0.38) EPHX1MMP2DPP7PLA2G2A
SCHEMBL13431642 0.82 CASP2 (0.47) EPHX1ACHEMMP2EPHX2
SCHEMBL15104585 0.82 EPHX2 (0.47) EPHX1ACHEMMP2ALOX15EPHX2
SCHEMBL11524825 0.82 EPHX1 (0.48) EPHX1ACHEMMP2EPHX2ZDHHC20
SCHEMBL5177522 0.79 MMP1 (0.33) MMP2
SCHEMBL5175882 0.78 ALDH1A1 (0.37)
SCHEMBL1264732 0.77 EPHX1 (0.52) EPHX1ACHEMMP2DPP7GRIN2D
SCHEMBL6129741 0.76 EPHX1 (0.61) EPHX1ACHEMMP2EPHX2PLA2G2A
SCHEMBL15104604 0.76 PLA2G2A (0.57) EPHX1EPHX2ZDHHC20ZDHHC2PLA2G2A
SCHEMBL15104686 0.76 PLA2G2A (0.57) EPHX1EPHX2ZDHHC20ZDHHC2PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
US-20030129520-A1 Using graft polymer on etched or anodized aluminum substrate FUJIFILM CORPORATION (JP) 2003-07-10 US disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed