Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615902 | 0.81 | BRD4 (0.46) | ABL1RXFP1CYP2C9 | |
| SCHEMBL4616052 | 0.79 | ALDH1A1 (0.43) | CYP3A4CYP2D6 | |
| SCHEMBL4614158 | 0.76 | NPC1 (0.42) | CYP3A4CYP2D6 | |
| SCHEMBL4616291 | 0.76 | AMY1A (0.50) | — | |
| SCHEMBL5282035 | 0.74 | RXFP1 (0.45) | HSD17B1HSD17B2ABL1RXFP1CYP3A4 | |
| SCHEMBL5282033 | 0.74 | RXFP1 (0.45) | HSD17B1HSD17B2ABL1RXFP1CYP3A4 | |
| SCHEMBL10913915 | 0.69 | HSD17B2 (0.47) | HSD17B1HSD17B2CYP3A4CYP2C9FYN | |
| SCHEMBL20476664 | 0.66 | KMT2A (0.69) | HSD17B1HSD17B2CYP3A4CYP2C9 | |
| SCHEMBL69369 | 0.65 | HSD17B1 (0.88) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL29551999 | 0.65 | HSD17B1 (0.88) | HSD17B1HSD17B2CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | claimed |