Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614158 | 0.96 | NPC1 (0.42) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL4616837 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10ADORA2B | |
| SCHEMBL4614104 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EKMT2AEGFR | |
| SCHEMBL4617337 | 0.81 | IDO1 (0.42) | ALDH1A1KMT2ANPSR1L3MBTL1EGFR | |
| SCHEMBL4622100 | 0.79 | GSTP1 (0.44) | ALDH1A1HPGDKDM4EKMT2ACYP1A2 | |
| SCHEMBL5289255 | 0.79 | HSD17B1 (0.44) | CYP3A4CYP2D6 | |
| SCHEMBL4615902 | 0.79 | BRD4 (0.46) | ALDH1A1KDM4EHSD17B10KMT2ABRD4 | |
| SCHEMBL4616586 | 0.78 | ADORA3 (0.48) | ALDH1A1KDM4EKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL11400687 | 0.76 | L3MBTL1 (0.47) | ALDH1A1KDM4ETSHRHSD17B10KMT2A | |
| SCHEMBL28839894 | 0.76 | ALOX12 (0.44) | ALDH1A1HPGDKDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | claimed |
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | claimed |
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | claimed |
| US-7291183-B2 | Agent and method for dyeing keratin fibers | WELLA AG (DE) | 2007-11-06 | — | — | US | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | claimed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | claimed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | claimed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | claimed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | claimed |
| EP-1599179-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| EP-1699426-A1 | AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2006-09-13 | — | — | EP | claimed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | claimed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | claimed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | claimed |
| EP-1599179-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2005-11-30 | — | — | EP | claimed |
| WO-2005060927-A1 | AGENT AND METHOD FOR OXIDATIVELY DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | claimed |
| WO-2004078153-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | claimed |
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | disclosed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-7291183-B2 | Agent and method for dyeing keratin fibers | WELLA AG (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| WO-2006094217-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | disclosed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | disclosed |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | Wella GmbH (DE) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | KRT18, GPX4, NOX4 | ALDH1A1 727/4885HPGD 1038/4885KDM4E 1120/4885 |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | ALDH1A1 137/4885HPGD 237/4885KDM4E 1510/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | ALDH1A1 494/4885HPGD 91/4885KDM4E 1848/4885 |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | KRT18, KIT, CKMT1A; CKMT1B | ALDH1A1 129/4885HPGD 220/4885KDM4E 1324/4885 |
| US-20060010616-A1 | Agent and method for dyeing keratin fibers | KRT18, KIT, MKI67 | ALDH1A1 561/4885HPGD 755/4885KDM4E 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.