Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105948 | 0.84 | CSF1R (0.51) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL1447775 | 0.83 | LMNA (0.48) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL27534143 | 0.76 | CSF1R (0.47) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL11022041 | 0.76 | CSF1R (0.53) | CSF1RLMNARAB9ANPC1HTT | |
| SCHEMBL4060937 | 0.75 | CSF1R (0.58) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL11016941 | 0.73 | CSF1R (0.57) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL7221487 | 0.71 | HTT (0.61) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL27534146 | 0.70 | CSF1R (0.47) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL6596929 | 0.67 | CSF1R (0.36) | CSF1RDHODHLMNARAB9ANPC1 | |
| SCHEMBL754481 | 0.67 | SMN1; SMN2 (0.54) | CSF1RLMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828183-A1 | 4- (4- (IMIDAZOL-4-YL) PYRIMIDIN-2-YLAMINO) BENZAMIDES AS CDK INHIBITORS | AstraZeneca AB (SE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006064251-A1 | 4- (4- (IMIDAZOL-4-YL) PYRIMIDIN-2-YLAMINO) BENZAMIDES AS CDK INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |