Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97203 | 0.94 | CHRM5 (0.42) | CHRM5NPSR1DCTPP1HDAC7FAAH | |
| SCHEMBL97064 | 0.80 | HCRTR1 (0.47) | CHRM5DCTPP1HDAC7FAAHMGLL | |
| SCHEMBL17543578 | 0.74 | CMA1 (0.40) | CHRM5 | |
| SCHEMBL17543429 | 0.74 | CHRM5 (0.43) | CHRM5 | |
| SCHEMBL95681 | 0.73 | HDAC7 (0.46) | CHRM5DCTPP1HDAC7FAAHMGLL | |
| SCHEMBL96096 | 0.71 | FAAH (0.43) | CHRM5ACHEDCTPP1HDAC7FAAH | |
| SCHEMBL97124 | 0.71 | FAAH (0.43) | ACHEDCTPP1HDAC7FAAHMGLL | |
| SCHEMBL17543189 | 0.69 | CHRM5 (0.39) | CHRM5HCRTR1HCRTR2 | |
| SCHEMBL5769842 | 0.67 | MGLL (0.65) | DCTPP1HDAC7FAAHMGLL | |
| SCHEMBL24115682 | 0.65 | CA1 (0.38) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |