SCHEMBL24115682

SCHEMBL24115682

O=S(=O)(Oc1ccc(-c2ccc(-c3ccccc3)cc2)c2ccccc12)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA9 Q16790 4/20 0.38
CA12 O43570 3/20 0.36
PTPN1 P18031 2/20 0.36
KIF11 P52732 1/20 0.35
BACE1 P56817 1/20 0.35
CYP2D6 P10635 1/20 0.35
PTGS2 P35354 1/20 0.34
MEN1 O00255 1/20 0.34
APAF1 O14727 1/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
XBP1 P17861 1/20 0.34
PTBP1 P26599 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
GALK1 P51570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23020149 0.90 ALOX15 (0.36) MEN1LMNAKMT2AATML3MBTL1
SCHEMBL9470141 0.89 GPR3 (0.37) CA1CA2CA9MEN1KMT2A
SCHEMBL6851155 0.87 MEN1 (0.38) CA1CA2CA9MEN1KMT2A
SCHEMBL10017163 0.85 ADORA2A (0.34) PTPN1MEN1KMT2APTGDR2ADORA2A
SCHEMBL29458425 0.83 SLC6A9 (0.44) CA1CA2CA9PTPN1KIF11
SCHEMBL15116983 0.80 BACE1 (0.37) CA1CA2CA9PTPN1BACE1
SCHEMBL29706003 0.79 MEN1 (0.42) MEN1KMT2ADRD2DRD1DRD4
SCHEMBL203899 0.79 MEN1 (0.42) MEN1KMT2ADRD2DRD1DRD4
SCHEMBL20987749 0.79 ADORA2A (0.37) BACE1PTGDR2ADORA2AADORA1DRD2
SCHEMBL8636736 0.79 IDO1 (0.46) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3381068-B1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS NOVALED GMBH (DE) 2021-12-22 EP disclosed