Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5290923 | 0.88 | LOXL2 (0.40) | MPOFDFT1LOXL2MMP2MMP9 | |
| SCHEMBL5290930 | 0.84 | FDFT1 (0.39) | MPOFDFT1LOXL2MMP2MMP9 | |
| SCHEMBL5298422 | 0.83 | ALDH1A1 (0.39) | MPOFDFT1LOXL2MMP2MMP9 | |
| SCHEMBL5293411 | 0.81 | FDFT1 (0.41) | MPOFDFT1LOXL2MMP2MMP9 | |
| SCHEMBL5305528 | 0.80 | SMN1; SMN2 (0.44) | MPOFDFT1MMP2MMP9ALDH1A1 | |
| SCHEMBL5304439 | 0.80 | FDFT1 (0.42) | MPOFDFT1LOXL2MMP2MMP9 | |
| SCHEMBL5299870 | 0.79 | KCNH3 (0.41) | ALDH1A1SCN9A | |
| SCHEMBL5305531 | 0.78 | FDFT1 (0.37) | MPOFDFT1MMP2MMP9MMP14 | |
| SCHEMBL5288569 | 0.77 | GCK (0.50) | ALDH1A1GCK | |
| SCHEMBL5292190 | 0.72 | CA12 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |