Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5290923 | 0.89 | LOXL2 (0.40) | ALDH1A1FDFT1MPOMMP2MMP3 | |
| SCHEMBL5289981 | 0.83 | MPO (0.42) | ALDH1A1FDFT1MPOMMP2MMP3 | |
| SCHEMBL5290930 | 0.82 | FDFT1 (0.39) | ALDH1A1FDFT1MPOMMP2MMP3 | |
| SCHEMBL5299870 | 0.80 | KCNH3 (0.41) | ALDH1A1SCN9AKDM4EMEN1KMT2A | |
| SCHEMBL5305528 | 0.79 | SMN1; SMN2 (0.44) | ALDH1A1FDFT1MPOMMP2MMP9 | |
| SCHEMBL5305620 | 0.79 | GCK (0.38) | ALDH1A1FDFT1MPOMMP2MMP3 | |
| SCHEMBL5304439 | 0.76 | FDFT1 (0.42) | ALDH1A1FDFT1MPOMMP2MMP3 | |
| SCHEMBL5288569 | 0.76 | GCK (0.50) | ALDH1A1GCK | |
| SCHEMBL5293411 | 0.75 | FDFT1 (0.41) | ALDH1A1FDFT1MPOMMP2MMP3 | |
| SCHEMBL5305531 | 0.75 | FDFT1 (0.37) | ALDH1A1FDFT1MPOMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |