Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527888 | 0.93 | MAPT (0.45) | GAAGPR27NPC1AVPR2RAB9A | |
| SCHEMBL529002 | 0.89 | LMNA (0.50) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL529590 | 0.89 | LMNA (0.49) | GAAGPR27AVPR2HDAC1HDAC8 | |
| SCHEMBL527865 | 0.88 | SMO (0.47) | GPR27ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL528331 | 0.88 | FFAR1 (0.49) | GAANPC1RAB9AALDH1A1HTT | |
| SCHEMBL528626 | 0.88 | ALDH1A1 (0.46) | GAAGPR27NPC1AVPR2HDAC1 | |
| SCHEMBL528931 | 0.87 | MAPT (0.47) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL528041 | 0.85 | HTT (0.56) | GAAGPR27ALDH1A1HTTMAPT | |
| SCHEMBL529592 | 0.83 | MAPT (0.55) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL528022 | 0.83 | LMNA (0.49) | GPR27NPC1AVPR2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |