SCHEMBL529289

SCHEMBL529289

Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1O

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.65
ADRB1 P08588 1/20 0.65
DNMT3B Q9UBC3 2/20 0.55
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
PNP P00491 1/20 0.50
TP53 P04637 1/20 0.50
HTT P42858 1/20 0.50
PDE4D Q08499 1/20 0.50
PDE3A Q14432 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
TK1 P04183 1/20 0.49
FPR2 P25090 1/20 0.49
ALOX12 P18054 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL530280 1.00 DNMT1 (0.65) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
Phosphoric Acid SCHEMBL6460717 0.95 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983766 0.89 DNMT1 (0.66) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983760 0.89 DNMT1 (0.66) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL24141674 0.86 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL22299584 0.86 DNMT1 (0.64) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
Ibacitabine SCHEMBL244921 0.86 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
Cytochlor SCHEMBL21423105 0.86 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
Ibacitabine SCHEMBL21423094 0.86 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL9692250 0.86 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125669-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION UNIVERSITAT POMPEU FABRA (ES) 2026-05-07 US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4599047-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION Universitat Pompeu Fabra (ES) 2025-08-13 EP claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
WO-2024074709-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION UNIVERSITAT POMPEU FABRA (ES) 2024-04-11 WO claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
EP-4114417-A2 THERAPEUTIC AGENTS AND CONJUGATES THEREOF Beijing Xuanyi Pharmasciences Co., Ltd. (CN) 2023-01-11 EP claimed
CN-115427051-A Therapeutic agents and conjugates thereof 北京轩义医药科技有限公司 2022-12-02 CN claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
WO-2003057822-A2 MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY OPTIMAL PRESENTATION OF 5' ENDS HYBRIDON, INC. (US) 2003-07-17 WO claimed
WO-2003035836-A2 MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS BY OPTIMAL PRESENTATION OF 5' ENDS HYBRIDON INC. (US) 2003-05-01 WO claimed
US-6548252-B1 Electrochemically analyzing samples from selected areas of the body of a living organism for elevated free levels of nucleotide excision products resulting from DNA or RNA damage ESA, INC. 2003-04-15 US claimed
EP-1226238-A2 METHOD FOR CREATING DIVERGENT POPULATIONS OF NUCLEIC ACID MOLECULES AND PROTEINS Cytos Biotechnology AG (CH) 2002-07-31 EP claimed
WO-2001030989-A2 METHOD FOR CREATING DIVERGENT POPULATIONS OF NUCLEIC ACID MOLECULES AND PROTEINS CYTOS BIOTECHNOLOGY AG (US) 2001-05-03 WO claimed
US-6132776-A ASSAYS FOR IDENTIFYING NUCLEOSIDE ANALOGS FOR THERAPY OF HIV(HUMAN IMMUNODEFICIENCY VIRUS)-INFECTED INDIVIDUALS UNIVERSITY OF WASHINGTON (US) 2000-10-17 US claimed
EP-0767842-B1 METHODS OF SCREENING FOR NUCLEOSIDE ANALOGS THAT ARE INCORPORATED BY HIV REVERSE TRANSCRIPTASE AND CAUSE INCORRECT BASE PAIRING UNIV WASHINGTON (US) 2000-09-27 EP claimed
EP-1004675-A2 Methods of screening for nucleoside analogs that are incorporated by HIV reverse transcriptase and cause incorrect base pairing DARWIN MOLECULAR CORPORATION (US) 2000-05-31 EP claimed
EP-0767842-A1 METHODS OF SCREENING FOR NUCLEOSIDE ANALOGS THAT ARE INCORPORATED BY HIV REVERSE TRANSCRIPTASE AND CAUSE INCORRECT BASE PAIRING DARWIN MOLECULAR CORPORATION (US) 1997-04-16 EP claimed
WO-1996000797-A1 METHODS OF SCREENING FOR NUCLEOSIDE ANALOGS THAT ARE INCORPORATED BY HIV REVERSE TRANSCRIPTASE AND CAUSE INCORRECT BASE PAIRING DARWIN MOLECULAR CORP (US) 1996-01-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT DNMT1 384/4885ADRB1 4067/4885DNMT3B 303/4885
US-20260125669-A1 METHODS AND COMPOSITIONS FOR SYNTHETIC EVOLUTION POLM, CPSF6, CPSF1 DNMT1 3336/4885ADRB1 4865/4885DNMT3B 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.