Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306337 | 0.85 | TXNRD1 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTTXNRD1 | |
| SCHEMBL5293863 | 0.84 | AKR1B1 (0.46) | LMNAMAPTMAOBMAPK1MEN1 | |
| SCHEMBL5298171 | 0.84 | TXNRD1 (0.45) | ALDH1A1LMNASMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL5293941 | 0.84 | TXNRD1 (0.43) | ALDH1A1LMNAMAPTHTTHSD17B10 | |
| SCHEMBL5290295 | 0.82 | MRGPRX4 (0.43) | SMN1; SMN2HTTTP53MEN1KMT2A | |
| SCHEMBL5295830 | 0.78 | L3MBTL1 (0.32) | L3MBTL1TXNRD1 | |
| SCHEMBL5298909 | 0.78 | POLB (0.45) | ALDH1A1L3MBTL1MAPTHTTHSD17B10 | |
| SCHEMBL5290581 | 0.78 | PLCG1 (0.47) | ALDH1A1LMNASMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL5301629 | 0.75 | KMT2A (0.41) | ALDH1A1SMN1; SMN2NPSR1L3MBTL1TXNRD1 | |
| SCHEMBL5297846 | 0.75 | AR (0.45) | LMNASMN1; SMN2L3MBTL1MAOBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |