Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | S100A9 | P06702 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294347 | 0.85 | ALDH1A1 (0.42) | TXNRD1HPGDMAPTALDH1A1LMNA | |
| SCHEMBL5293941 | 0.84 | TXNRD1 (0.43) | TXNRD1KDM4EHPGDMAPTALDH1A1 | |
| SCHEMBL5290295 | 0.82 | MRGPRX4 (0.43) | KDM4ESMN1; SMN2TP53 | |
| SCHEMBL5293863 | 0.82 | AKR1B1 (0.46) | GRM4KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL5290581 | 0.78 | PLCG1 (0.47) | TXNRD1GRM4HPGDMAPTALDH1A1 | |
| SCHEMBL5295830 | 0.78 | L3MBTL1 (0.32) | TXNRD1 | |
| SCHEMBL5298909 | 0.78 | POLB (0.45) | TXNRD1GRM4MAPTALDH1A1TP53 | |
| SCHEMBL5298171 | 0.76 | TXNRD1 (0.45) | TXNRD1GRM4HPGDMAPTALDH1A1 | |
| SCHEMBL5301629 | 0.75 | KMT2A (0.41) | TXNRD1GRM4ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL5297846 | 0.75 | AR (0.45) | HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |