Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5290581 | 0.89 | PLCG1 (0.47) | TXNRD1ALDH1A1L3MBTL1MAPTTP53 | |
| SCHEMBL5298171 | 0.87 | TXNRD1 (0.45) | POLBTXNRD1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL5293941 | 0.87 | TXNRD1 (0.43) | POLBTXNRD1ALDH1A1MAPTHTT | |
| SCHEMBL5295830 | 0.86 | L3MBTL1 (0.32) | POLBTXNRD1L3MBTL1 | |
| SCHEMBL5304080 | 0.84 | ALDH1A1 (0.51) | POLBALDH1A1MAPTBCHEACHE | |
| SCHEMBL5301629 | 0.83 | KMT2A (0.41) | TXNRD1ALDH1A1L3MBTL1TP53PLCG1 | |
| SCHEMBL5297846 | 0.80 | AR (0.45) | L3MBTL1CA1CA2CA9KMT2A | |
| SCHEMBL5290607 | 0.78 | ALDH1A1 (0.49) | TXNRD1ALDH1A1MAPTTP53HTT | |
| SCHEMBL5294347 | 0.78 | ALDH1A1 (0.42) | TXNRD1ALDH1A1L3MBTL1MAPTTP53 | |
| SCHEMBL5306337 | 0.78 | TXNRD1 (0.49) | TXNRD1ALDH1A1MAPTTP53GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |