Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | AMD1 | P17707 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982748 | 1.00 | ADORA3 (0.53) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL439797 | 1.00 | ADORA3 (0.53) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL439799 | 1.00 | ADORA3 (0.53) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL27054384 | 1.00 | ADORA3 (0.53) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL5982753 | 1.00 | ADORA3 (0.53) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| Phosphoric Acid SCHEMBL16871802 | 0.96 | ADORA3 (0.50) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL443066 | 0.88 | TK1 (0.46) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL27053980 | 0.87 | AMD1 (0.43) | ADORA3ADORA2AAMD1 | |
| SCHEMBL5982026 | 0.87 | LMNA (0.45) | ADORA3ADORA2ADNMT1ADRB1LMNA | |
| SCHEMBL5982032 | 0.87 | LMNA (0.45) | ADORA3ADORA2ADNMT1ADRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012016145-A2 | MITOCHONDRIAL APOPTOSIS-INDUCED INFLAMMATION | CEDARS-SINAI MEDICAL CENTER (US) | 2012-02-02 | — | — | WO | disclosed |