SCHEMBL5295877

SCHEMBL5295877

CCN(CC(=O)O)S(=O)(=O)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.54
RORC P51449 9/20 0.50
HSP90AA1 P07900 1/20 0.49
NR1I2 O75469 1/20 0.43
RORA P35398 1/20 0.43
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
RORB Q92753 1/20 0.43
NR1H4 Q96RI1 1/20 0.43
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192672 0.88 CNR2 (0.65) CNR2RORCHSP90AA1NR1I2RORA
SCHEMBL5279670 0.87 RORC (0.53) CNR2RORCHSP90AA1NR1I2RORA
SCHEMBL5281753 0.85 CNR2 (0.55) CNR2RORCHSP90AA1NR1I2RORA
SCHEMBL5329535 0.80 RAB9A (0.53) CNR2RORCHSP90AA1NR1I2RORA
SCHEMBL5966751 0.79 HSP90AA1 (0.51) CNR2RORCHSP90AA1
SCHEMBL31519008 0.79 HSP90AA1 (0.55) CNR2RORCHSP90AA1KMT2A
SCHEMBL10597184 0.78 HSP90AA1 (0.58) CNR2RORCHSP90AA1NR1I2RORA
SCHEMBL31165765 0.77 CNR2 (0.51) CNR2RORCNR1I2RORANR1H2
SCHEMBL5279949 0.77 RORC (0.50) RORCHSP90AA1NR1I2RORANR1H2
SCHEMBL8527678 0.76 CNR2 (0.55) CNR2RORCHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007001335-A2 RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2007-01-04 WO disclosed
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity VICURON PHARMACEUTICALS INC. (US) 2006-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity CLSPN, LMAN2, RPN2 CNR2 3256/4885RORC 3389/4885HSP90AA1 1124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.