Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180539 | 0.87 | HSP90AA1 (0.49) | RAB9AHSP90AA1RORCCNR2POLB | |
| SCHEMBL5281753 | 0.81 | CNR2 (0.55) | HSP90AA1RORCCNR2ALDH1A1POLB | |
| SCHEMBL5295877 | 0.80 | CNR2 (0.54) | HSP90AA1RORCCNR2NR1I2RORA | |
| SCHEMBL5324937 | 0.78 | RAB9A (0.63) | RAB9AALDH1A1SMN1; SMN2KEAP1ESR1 | |
| SCHEMBL5279670 | 0.77 | RORC (0.53) | RAB9AHSP90AA1RORCCNR2SMN1; SMN2 | |
| SCHEMBL31519008 | 0.75 | HSP90AA1 (0.55) | HSP90AA1RORCCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27783120 | 0.75 | RAB9A (0.44) | RAB9AALDH1A1POLB | |
| SCHEMBL11871750 | 0.75 | RAB9A (0.47) | RAB9AALDH1A1POLB | |
| SCHEMBL10597184 | 0.75 | HSP90AA1 (0.58) | HSP90AA1RORCCNR2NR1I2RORA | |
| SCHEMBL31165765 | 0.74 | CNR2 (0.51) | RORCCNR2NR1I2RORANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | RAB9A 20/4885HSP90AA1 1124/4885RORC 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.