Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528331 | 0.91 | FFAR1 (0.49) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL527865 | 0.89 | SMO (0.47) | MAPTSMN1; SMN2LMNATP53MEN1 | |
| SCHEMBL529730 | 0.89 | MAPT (0.58) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL527888 | 0.89 | MAPT (0.45) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL529397 | 0.88 | MAPT (0.57) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL528660 | 0.87 | L3MBTL1 (0.48) | MAPTRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL529051 | 0.86 | MAPT (0.71) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL528124 | 0.86 | KMT2A (0.53) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL528251 | 0.86 | MAPT (0.41) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL528985 | 0.86 | MAPT (0.54) | MAPTRAB9ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |