Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528331 | 0.92 | FFAR1 (0.49) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL528658 | 0.90 | ALDH1A1 (0.53) | SMOKMT2ACNR1CNR2MEN1 | |
| SCHEMBL529592 | 0.89 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL528672 | 0.89 | SMO (0.46) | SMOKMT2ACNR1CNR2MEN1 | |
| SCHEMBL528323 | 0.88 | GAA (0.44) | KMT2ACNR1MEN1MAPTALDH1A1 | |
| SCHEMBL528660 | 0.88 | L3MBTL1 (0.48) | KMT2AMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL529639 | 0.87 | MAPT (0.55) | SMOKMT2ACNR1CNR2MEN1 | |
| SCHEMBL528124 | 0.87 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL528251 | 0.87 | MAPT (0.41) | KMT2AMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL527894 | 0.86 | RXFP1 (0.49) | KMT2AMEN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |