Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768494 | 0.89 | DAGLA (0.57) | DAGLACES1HSD11B1ALDH1A1SMO | |
| SCHEMBL8119163 | 0.85 | SCN9A (0.55) | DAGLACES1HSD11B1ALDH1A1KDM4E | |
| SCHEMBL28756282 | 0.84 | MKNK1 (0.50) | DAGLACES1ALDH1A1KDM4ELMNA | |
| SCHEMBL3718120 | 0.82 | ENPP3 (0.54) | DAGLANR4A2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9813483 | 0.79 | CES1 (0.60) | CES1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8552635 | 0.79 | EDNRA (0.43) | DAGLACES1HSD11B1ALDH1A1KDM4E | |
| SCHEMBL8146467 | 0.77 | CA2 (0.53) | — | |
| SCHEMBL8147535 | 0.77 | RXFP1 (0.47) | DAGLAHSD11B1ALDH1A1KDM4ELMNA | |
| SCHEMBL14564373 | 0.75 | SCN9A (0.62) | DAGLACES1ALDH1A1KDM4ESCN9A | |
| SCHEMBL8149304 | 0.74 | CA2 (0.55) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| CN-1834091-A | Sustituted Gly derivative for treating diabetes and adiposis | SHENG ZELIN (CN) | 2006-09-20 | — | — | CN | disclosed |