Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147535 | 0.80 | RXFP1 (0.47) | DAGLAKDM4EALDH1A1POLBATR | |
| SCHEMBL5296166 | 0.79 | DAGLA (0.57) | ENPP3ENPP1DAGLAKDM4EALDH1A1 | |
| SCHEMBL890515 | 0.74 | PTGS2 (0.49) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL29788178 | 0.74 | PTGS2 (0.49) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8138559 | 0.73 | PTGS2 (0.47) | ENPP3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8658514 | 0.72 | PTGS2 (0.62) | EDNRAKDM4EALDH1A1RAB9APTGS2 | |
| SCHEMBL29415408 | 0.72 | PTGS2 (0.61) | EDNRAKDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL937206 | 0.72 | PTGS2 (0.61) | EDNRAKDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL8146467 | 0.71 | CA2 (0.53) | PTGS2 | |
| SCHEMBL8552633 | 0.70 | NR4A2 (0.62) | KDM4EALDH1A1RAB9APOLBATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |