Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308272 | 0.89 | TSHR (0.51) | MTNR1AMTNR1BKMT2AKDM4EALDH1A1 | |
| SCHEMBL3863503 | 0.71 | ALOX5 (0.47) | MTNR1AMTNR1BNPC1KMT2AGAA | |
| SCHEMBL3099150 | 0.71 | HPGD (0.50) | NPC1TDP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11665567 | 0.68 | HTR2A (0.53) | MTNR1AMTNR1BDRD2KMT2AKDM4E | |
| SCHEMBL6014774 | 0.68 | KDM4E (0.61) | MTNR1AMTNR1BTDP1MEN1KMT2A | |
| SCHEMBL17102815 | 0.66 | KDM4E (0.59) | MTNR1AMTNR1BTDP1MEN1KMT2A | |
| SCHEMBL18229465 | 0.66 | OXER1 (0.64) | MTNR1AMTNR1BTDP1GAAKDM4E | |
| SCHEMBL13097743 | 0.66 | ALDH1A1 (0.53) | NPC1MEN1KMT2AGAAKDM4E | |
| SCHEMBL5465561 | 0.65 | MEN1 (0.65) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL2730991 | 0.65 | PTGS2 (0.52) | NPC1KDM4EALDH1A1MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005779-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-01-11 | — | — | WO | claimed |