SCHEMBL98450

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL97250	0.84	BRD4 (0.48)	ALDH1A1L3MBTL1KDM4EGAAPOLB
	SCHEMBL5297293	0.83	BRD4 (0.47)	ALDH1A1L3MBTL1KDM4EGAAPOLB
	SCHEMBL98191	0.82	MTNR1A (0.34)	ALDH1A1KDM4EHPGDATMKMT2A
	SCHEMBL5297286	0.82	BRD4 (0.46)	ALDH1A1L3MBTL1KDM4EGAAPOLB
	SCHEMBL96332	0.82	ALDH1A1 (0.38)	ALDH1A1L3MBTL1KDM4EHPGDGAA
	SCHEMBL5289604	0.78	BRD4 (0.43)	ALDH1A1L3MBTL1ATMGAAPOLB
	SCHEMBL97131	0.78	ALDH1A1 (0.43)	ALDH1A1KDM4EHPGDPOLBKMT2A
	SCHEMBL96649	0.73	NPC1 (0.35)	ALDH1A1KDM4EHPGDATMGAA
	SCHEMBL98006	0.73	PARP1 (0.32)	ALDH1A1KDM4EHPGDGAAGLA
	SCHEMBL98120	0.72	CYP11B1 (0.40)	ALDH1A1HPGDKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.