Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326545 | 0.91 | PTGS2 (0.39) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL5288972 | 0.90 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14622895 | 0.88 | PTGS2 (0.41) | KMT2APOLBALDH1A1HSD17B10MAPT | |
| SCHEMBL5331474 | 0.87 | PTGS2 (0.38) | MEN1KMT2AMAPTKDM4EPTGS2 | |
| SCHEMBL5325697 | 0.86 | RAD51 (0.40) | PTGS2HTTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL5324999 | 0.86 | PTGS2 (0.35) | POLBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5325002 | 0.86 | PTGS2 (0.35) | POLBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5327308 | 0.85 | HTT (0.37) | MEN1KMT2AALDH1A1MAPTPTGS2 | |
| SCHEMBL5327304 | 0.85 | PTGS2 (0.35) | KMT2AALDH1A1MAPTKDM4EPTGS2 | |
| SCHEMBL5324682 | 0.84 | THRB (0.35) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |