Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326343 | 0.88 | THRB (0.36) | THRBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5331474 | 0.84 | PTGS2 (0.38) | THRBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5297375 | 0.84 | MEN1 (0.42) | PTGS2HTTSMN1; SMN2LMNACYP2C9 | |
| SCHEMBL5325697 | 0.83 | RAD51 (0.40) | THRBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5320991 | 0.83 | THRB (0.33) | THRBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5323775 | 0.82 | ALDH1A1 (0.39) | THRBPTGS2HTTLMNAPTGS1 | |
| SCHEMBL5326545 | 0.81 | PTGS2 (0.39) | THRBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5325596 | 0.81 | MEN1 (0.41) | HTTALDH1A1MEN1KMT2A | |
| SCHEMBL5288972 | 0.81 | MEN1 (0.40) | THRBPTGS2HTTSMN1; SMN2LMNA | |
| SCHEMBL5320985 | 0.81 | PTGS2 (0.43) | THRBPTGS2HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |