Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.65 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.65 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.58 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090142 | 0.93 | HSD17B1 (0.58) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL5582735 | 0.93 | CA1 (0.67) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL17213443 | 0.92 | HPGD (0.62) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL7376311 | 0.92 | HSD17B1 (0.57) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL8703995 | 0.91 | KDM4E (0.61) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL529976 | 0.91 | KDM4E (0.71) | HSD17B1HSD17B2MCHR1HPGDKDM4E | |
| Water SCHEMBL11232730 | 0.90 | HSD17B1 (0.56) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| Water SCHEMBL11232726 | 0.90 | HSD17B1 (0.56) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL15480658 | 0.89 | CA1 (0.70) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 | |
| SCHEMBL5582630 | 0.89 | MCHR1 (0.56) | HSD17B1HSD17B2MCHR1HSP90AA1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |