Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288032 | 0.83 | MAPK14 (0.56) | ALDH1A1MAPK14 | |
| SCHEMBL5293741 | 0.81 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL27727217 | 0.79 | ALDH1A1 (0.48) | MAPK1MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL27727317 | 0.77 | ALDH1A1 (0.45) | MAPK1MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL27706506 | 0.75 | KIF11 (0.57) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL20951663 | 0.75 | CA1 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL5286643 | 0.74 | MAPK1 (0.47) | ALDH3A1MAPK1MAPTALDH1A1TDP1 | |
| SCHEMBL5281273 | 0.72 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL2319223 | 0.71 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL4219691 | 0.70 | MAPK14 (0.74) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007000337-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | disclosed |