Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297206 | 0.83 | GABRP (0.43) | SMN1; SMN2TSHRHSD17B10GABRA1GABRB2 | |
| SCHEMBL13862488 | 0.81 | GABRA1 (0.46) | HSD17B1SMN1; SMN2TSHRHSD17B10PPARG | |
| SCHEMBL28184235 | 0.78 | GABRA1 (0.41) | MAPTGABRA1GABRB2ALDH1A1 | |
| SCHEMBL3117998 | 0.75 | CYP1A2 (0.48) | SMN1; SMN2TDP1TSHRHSD17B10GABRA1 | |
| SCHEMBL7177477 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL4777676 | 0.73 | MAPT (0.47) | HSD17B1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL28690580 | 0.72 | CNR2 (0.35) | HSD17B1CA12SMN1; SMN2MAPTTSHR | |
| SCHEMBL9217873 | 0.72 | HSD17B1 (0.58) | HSD17B1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL4677431 | 0.72 | HSD17B1 (0.44) | HSD17B1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL27075327 | 0.72 | CLCN2 (0.36) | HSD17B1MAPTCYP2C9TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | claimed |
| US-20060283469-A1 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2006-12-21 | — | — | US | claimed |
| US-11317649-B2 | Material for inclusion in a smoking article | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2022-05-03 | — | — | US | disclosed |
| US-11246335-B2 | Material for inclusion in a smoking article | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-20200359673-A1 | Material for Inclusion in a Smoking Article | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2020-11-19 | — | — | US | disclosed |
| EP-3737247-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | British American Tobacco (Investments) Limited (GB) | 2020-11-18 | — | — | EP | disclosed |
| US-10765141-B2 | Material for inclusion in a smoking article | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2020-09-08 | — | — | US | disclosed |
| CN-105357990-B | Material for inclusion in a smoking article | 英美烟草(投资)有限公司 | 2020-03-31 | — | — | CN | disclosed |
| US-10271573-B2 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2019-04-30 | — | — | US | disclosed |
| EP-3242568-B1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | BRITISH AMERICAN TOBACCO INVESTMENTS LTD (GB) | 2018-10-31 | — | — | EP | disclosed |
| EP-3242567-B1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | BRITISH AMERICAN TOBACCO INVESTMENTS LTD (GB) | 2018-10-17 | — | — | EP | disclosed |
| EP-3242568-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | British American Tobacco (Investments) Ltd (GB) | 2017-11-15 | — | — | EP | disclosed |
| EP-3242567-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | British American Tobacco (Investments) Ltd (GB) | 2017-11-15 | — | — | EP | disclosed |
| US-20160219926-A1 | Material for Inclusion in a Smoking Article | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2016-08-04 | — | — | US | disclosed |
| WO-2016110689-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2016-07-14 | — | — | WO | disclosed |
| WO-2016110688-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2016-07-14 | — | — | WO | disclosed |
| EP-3019040-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | British American Tobacco (Investments) Limited (GB) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015004483-A1 | MATERIAL FOR INCLUSION IN A SMOKING ARTICLE | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | disclosed |
| US-20060283469-A1 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2006-12-21 | — | — | US | disclosed |