Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15455834 | 0.91 | LMNA (0.49) | PKMMAOAMAOBCYP1A2CYP2C19 | |
| SCHEMBL6093718 | 0.89 | KDM4E (0.42) | PKMMAOAMAOBALDH1A1HSD17B10 | |
| SCHEMBL3420229 | 0.83 | CYP1A2 (0.47) | PKMMAOAMAOBCYP1A2CYP2C19 | |
| SCHEMBL2507511 | 0.80 | MAOA (0.48) | PKMMAOAMAOBCYP1A2CYP2C19 | |
| SCHEMBL1668866 | 0.76 | HDAC1 (0.46) | PKMMAOAMAOBCYP1A2CYP2C19 | |
| SCHEMBL5644365 | 0.76 | KDM4E (0.44) | CYP1A2CYP2C19ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL5310259 | 0.75 | CYP1A2 (0.41) | PKMMAOAMAOBCYP1A2CYP2C19 | |
| SCHEMBL15320367 | 0.75 | ALDH1A1 (0.44) | CYP1A2SRD5A2ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL2553621 | 0.75 | PKM (0.44) | PKMMAOAMAOBSRD5A2ALDH1A1 | |
| SCHEMBL1671403 | 0.74 | DPP4 (0.47) | CYP1A2CYP2C19ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756069-A4 | HIV INTEGRASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2007-11-28 | — | — | EP | disclosed |
| EP-1756069-A2 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2007-02-28 | — | — | EP | disclosed |
| US-7115601-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-03 | — | — | US | disclosed |
| WO-2005115398-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050261322-A1 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261322-A1 | HIV integrase inhibitors | TYMP, PAICS, TYMS | PKM 3820/4885MAOA 2101/4885MAOB 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.