Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306282 | 0.84 | HSP90AA1 (0.41) | AOC3CHRM3L3MBTL1MMP2 | |
| SCHEMBL5304740 | 0.80 | AKR1C3 (0.43) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5304827 | 0.79 | PRKCZ (0.41) | MAPK1SMN1; SMN2MMP2 | |
| SCHEMBL5309071 | 0.77 | SLC6A4 (0.42) | GPR139AOC3SMN1; SMN2L3MBTL1MMP2 | |
| SCHEMBL5304270 | 0.75 | LMNA (0.52) | MAPK1 | |
| SCHEMBL10094585 | 0.74 | ADRA2C (0.51) | ADRA2CPTGDR2MAOB | |
| Maleic Acid SCHEMBL9879499 | 0.70 | ADRA2C (0.49) | ADRA2CGPR139ADAMTS4CHRM3PTGDR2 | |
| SCHEMBL6164469 | 0.70 | HPGDS (0.46) | ADRA2CPTGDR2HPGDSMAOBKAT6A | |
| SCHEMBL6165960 | 0.70 | TNF (0.48) | ADRA2CPTGDR2HPGDSMAOBTNF | |
| SCHEMBL7108450 | 0.69 | ADRA2C (0.44) | ADRA2CPTGDR2HPGDSMAOBKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |