Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303985 | 0.87 | ALDH1A1 (0.53) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5303048 | 0.82 | GRM5 (0.54) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5306988 | 0.81 | NPC1 (0.47) | TSHRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5304381 | 0.81 | NTRK1 (0.51) | MAPTALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL5311060 | 0.78 | MAPT (0.49) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL5306559 | 0.77 | KDM4E (0.47) | TSHRL3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL5306214 | 0.77 | RAB9A (0.57) | MAPTSMN1; SMN2NPC1RAB9AABCB1 | |
| Hydrochloric Acid SCHEMBL5370588 | 0.77 | RAB9A (0.56) | MAPTSMN1; SMN2NPC1RAB9AABCB1 | |
| SCHEMBL5306317 | 0.75 | MAPT (0.45) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL5326930 | 0.74 | MAPT (0.43) | MAPTKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |