Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5304367 | 0.81 | ALDH1A1 (0.44) | MAPTPOLBMALT1MEN1KMT2A | |
| SCHEMBL5311060 | 0.78 | MAPT (0.49) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5306317 | 0.78 | MAPT (0.45) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL13772498 | 0.77 | SMN1; SMN2 (0.49) | MAPTNAMPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5303985 | 0.76 | ALDH1A1 (0.53) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5301960 | 0.74 | TSHR (0.55) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5304381 | 0.74 | NTRK1 (0.51) | MAPTPOLBALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL13772494 | 0.74 | SOAT2 (0.52) | MAPTPOLBALDH1A1LMNANPSR1 | |
| SCHEMBL5303048 | 0.73 | GRM5 (0.54) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5306988 | 0.73 | NPC1 (0.47) | MAPTPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |