Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5306307 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL5326930 | 0.81 | MAPT (0.43) | ALDH1A1POLBRAB9AMAPTMEN1 | |
| SCHEMBL5303090 | 0.75 | MAPT (0.51) | ALDH1A1KDM4ERAB9ANPC1MAPT | |
| SCHEMBL5306582 | 0.75 | MAPT (0.41) | POLBRAB9AMAPTLMNANPSR1 | |
| SCHEMBL5303639 | 0.74 | LMNA (0.44) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL5307503 | 0.74 | MEN1 (0.38) | ALDH1A1KDM4EPOLBMAPTMEN1 | |
| SCHEMBL5306559 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL5307225 | 0.73 | MAPT (0.48) | ALDH1A1KDM4EPOLBMAPTMEN1 | |
| SCHEMBL5306913 | 0.73 | CDK2 (0.40) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL5311858 | 0.73 | LMNA (0.43) | KDM4EPOLBMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |