Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TLR3 | O15455 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865536 | 0.71 | NPC1 (0.42) | L3MBTL1TDP1HIF1APTPN1TLR3 | |
| SCHEMBL16694678 | 0.70 | HIF1A (0.49) | HIF1A | |
| SCHEMBL16694371 | 0.70 | PTPN1 (0.46) | HIF1APTPN1NPC1RAB9ABCHE | |
| SCHEMBL39472 | 0.69 | HPGD (0.78) | L3MBTL1HPGDALDH1A1TDP1HSPB1 | |
| SCHEMBL28056476 | 0.68 | L3MBTL1 (0.81) | L3MBTL1HPGDALDH1A1TDP1HSPB1 | |
| SCHEMBL5309484 | 0.68 | NPC1 (0.40) | L3MBTL1ALDH1A1TDP1HIF1APTPN1 | |
| SCHEMBL29084580 | 0.67 | HPGD (0.64) | L3MBTL1HPGDALDH1A1TDP1HSPB1 | |
| SCHEMBL12410975 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TDP1HIF1APTPN1TLR3 | |
| SCHEMBL5308046 | 0.64 | ALOX5 (0.44) | HPGDALDH1A1TDP1HIF1APTPN1 | |
| SCHEMBL8107182 | 0.64 | L3MBTL1 (0.56) | L3MBTL1HPGDALDH1A1TDP1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041463-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |