Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865536 | 0.72 | NPC1 (0.42) | NPC1RAB9APDE4DTDP1BCHE | |
| SCHEMBL16694371 | 0.71 | PTPN1 (0.46) | NPC1RAB9AGPR35PDE4DBCHE | |
| SCHEMBL16694678 | 0.69 | HIF1A (0.49) | KDM4ECA12CA1CA7CA9 | |
| SCHEMBL8680391 | 0.68 | TDP1 (0.51) | GPR35TDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL5308166 | 0.68 | L3MBTL1 (0.45) | NPC1RAB9ATDP1BCHEALDH1A1 | |
| SCHEMBL12410975 | 0.67 | ALDH1A1 (0.41) | NPC1RAB9APDE4DTDP1BCHE | |
| SCHEMBL17917509 | 0.67 | KMT2A (0.54) | GPR35TDP1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL12411214 | 0.66 | HIF1A (0.38) | NPC1RAB9APDE4DBCHEPTPN1 | |
| SCHEMBL5310251 | 0.66 | NPC1 (0.41) | NPC1RAB9APDE4DRARABCHE | |
| SCHEMBL14541016 | 0.66 | NPC1 (0.47) | NPC1RAB9APDE4DRARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |