Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638701 | 0.84 | ALDH1A1 (0.62) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL8889074 | 0.83 | KMT2A (0.80) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL9624375 | 0.81 | KMT2A (0.67) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL220059 | 0.81 | KMT2A (0.72) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL19221685 | 0.81 | HTT (0.72) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL2450123 | 0.81 | TSHR (0.58) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL11708769 | 0.81 | KMT2A (1.00) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL11123377 | 0.80 | CA2 (0.50) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL14856070 | 0.80 | TSHR (0.74) | KMT2ATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL8006673 | 0.80 | KMT2A (0.65) | KMT2ATSHRALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |
| EP-2203430-A1 | N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS | Abbott Laboratories (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009039135-A1 | N-PHENYL-DIOXO-HYDROPYRIMIDINES USEFUL AS HEPATITIS C VIRUS (HCV) INHIBITORS | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |