Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123655 | 0.85 | CA2 (0.51) | CA2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5444394 | 0.84 | CA2 (0.53) | CA2GAAKMT2AALDH1A1POLB | |
| SCHEMBL11123463 | 0.84 | ALDH1A1 (0.48) | CA2GAAPTK2KMT2AALDH1A1 | |
| SCHEMBL11120662 | 0.84 | MEN1 (0.55) | CA2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL2732048 | 0.82 | KMT2A (0.60) | CA2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL27575403 | 0.82 | MEN1 (0.54) | CA2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL31518457 | 0.81 | TSHR (0.57) | CA2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL3353838 | 0.81 | CA2 (0.57) | CA2KMT2AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL810 | 0.81 | KMT2A (0.58) | CA2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL594 | 0.81 | CA2 (0.53) | CA2GAAKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038636-B1 | SULFONAMIDE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-01-11 | — | — | EP | claimed |
| US-4321081-A | Ortho-(trifluoromethylsulfonamido)benzamides as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-23 | — | — | US | claimed |
| EP-0038636-A2 | Sulfonamide derivatives, compositions containing them and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-28 | — | — | EP | claimed |
| EP-0038636-B1 | SULFONAMIDE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-01-11 | — | — | EP | disclosed |
| US-4321081-A | Ortho-(trifluoromethylsulfonamido)benzamides as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-23 | — | — | US | disclosed |
| EP-0038636-A2 | Sulfonamide derivatives, compositions containing them and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-28 | — | — | EP | disclosed |