Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855473 | 0.77 | MAPT (0.71) | MAPTGRM5SMN1; SMN2POLBMEN1 | |
| SCHEMBL26673920 | 0.74 | MAPT (0.71) | MAPTHTTGRM5ALDH1A1KDM4E | |
| SCHEMBL5303048 | 0.74 | GRM5 (0.54) | P2RY14MAPTLMNAGRM5ALDH1A1 | |
| SCHEMBL26674089 | 0.74 | MAPT (0.71) | MAPTHTTGRM5ALDH1A1KDM4E | |
| SCHEMBL5304381 | 0.73 | NTRK1 (0.51) | MAPTGRM5ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL26856207 | 0.73 | GRM5 (0.64) | MAPTLMNAGRM5ALDH1A1KDM4E | |
| SCHEMBL5303985 | 0.72 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL5334228 | 0.72 | LMNA (0.44) | MAPTLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL26855558 | 0.71 | RAB9A (0.54) | MAPTLMNAGRM5ALDH1A1KDM4E | |
| SCHEMBL5330573 | 0.70 | MAPT (0.46) | MAPTLMNAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |