SCHEMBL5309684

SCHEMBL5309684

CC(COc1ccccc1)(NC(N)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 1/20 0.44
ALPI P09923 1/20 0.44
ALPG P10696 1/20 0.44
NPC1 O15118 2/20 0.42
CASP3 P42574 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
PPARA Q07869 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CXCR2 P25025 2/20 0.41
PARP10 Q53GL7 1/20 0.41
SSTR4 P31391 1/20 0.41
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
ALOX15 P16050 1/20 0.41
RAB9A P51151 2/20 0.40
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL798763 0.78 PPARA (0.42) ALPLALPIALPGNPC1CASP3
SCHEMBL14975398 0.77 NPC1 (0.46) NPC1CASP3SENP7MAPTSENP8
SCHEMBL2529604 0.76 EPHX1 (0.49) ALDH1A1L3MBTL1
SCHEMBL2517194 0.75 ALDH1A1 (0.60) ALPLALPIALPGPPARAALDH1A1
SCHEMBL3465226 0.75 PPARA (0.47) ALPLALPIALPGNPC1CASP3
SCHEMBL12468595 0.75 PARP10 (0.39) ALPLALPIALPGNPC1MAPT
SCHEMBL5724626 0.74 PPARA (0.58) PPARASSTR4ALOX15PPARG
SCHEMBL7805112 0.73 PPARA (0.49) ALPLALPIALPGMAPTPPARA
SCHEMBL6544667 0.73 ALDH1A1 (0.41) NPC1ALDH1A1PARP10MTNR1AMTNR1B
SCHEMBL7877370 0.72 MTNR1A (0.51) ALPLALPIALPGNPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007044309-A2 DEVICE AND METHOD FOR INHIBITING AGE COMPLEX FORMATION VASIX CORPORATION (US) 2007-04-19 WO disclosed