Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FABP2 | P12104 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309684 | 0.77 | ALPL (0.44) | NPC1RAB9ACASP3SENP7POLB | |
| SCHEMBL11363896 | 0.77 | PPARA (0.48) | NPC1RAB9ACASP3SENP7POLB | |
| SCHEMBL14975402 | 0.73 | PPARA (0.60) | NPC1RAB9ACASP3SENP7POLB | |
| SCHEMBL28451349 | 0.72 | POLB (0.56) | NPC1RAB9APOLBSMN1; SMN2KMT2A | |
| SCHEMBL10940237 | 0.72 | ALDH1A1 (0.43) | NPC1RAB9APOLBSMN1; SMN2PPARA | |
| SCHEMBL10940243 | 0.72 | ALDH1A1 (0.43) | NPC1RAB9APOLBSMN1; SMN2PPARA | |
| SCHEMBL3755534 | 0.72 | POLB (0.56) | NPC1RAB9APOLBSMN1; SMN2PPARA | |
| SCHEMBL3465226 | 0.72 | PPARA (0.47) | NPC1RAB9ACASP3SENP7POLB | |
| SCHEMBL787527 | 0.72 | CXCR2 (0.46) | — | |
| SCHEMBL28908852 | 0.72 | POLB (0.53) | NPC1RAB9APOLBSMN1; SMN2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2014-12-18 | — | — | US | disclosed |
| EP-2782902-A2 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | Fabricant, Jill, S. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078446-A2 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | AGER, BPGM, FOSB | NPC1 4757/4885RAB9A 1613/4885CASP3 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.