SCHEMBL5309690

SCHEMBL5309690

CC(CNC(N)=O)(Oc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.49
PPARA Q07869 3/20 0.49
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
PARP10 Q53GL7 2/20 0.39
BCAT2 O15382 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PRSS1 P07477 1/20 0.39
CTSG P08311 1/20 0.39
CTRB1 P17538 1/20 0.39
CMA1 P23946 1/20 0.39
ELANE P08246 1/20 0.39
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2517199 0.80 PPARG (0.54) PPARGPPARAADORA3PARP10MEN1
SCHEMBL7087893 0.79 PPARG (0.57) PPARGPPARAADORA3MEN1KMT2A
SCHEMBL14975402 0.78 PPARA (0.60) PPARGPPARANPC1POLBCASP3
SCHEMBL1960387 0.78 PPARG (0.62) PPARGPPARAADORA3MEN1KMT2A
SCHEMBL3975913 0.76 PPARG (0.54) PPARGPPARAADORA3MEN1KMT2A
SCHEMBL3465228 0.76 PPARG (0.58) PPARGPPARAADORA3MEN1KMT2A
SCHEMBL31550448 0.75 L3MBTL1 (0.55) PPARGPPARANPC1POLBRAB9A
SCHEMBL82055 0.75 PPARG (0.53) PPARGPPARAADORA3MEN1KMT2A
SCHEMBL5322591 0.75 PPARG (0.79) PPARGPPARA
SCHEMBL8935937 0.75 PPARG (0.53) PPARGPPARAADORA3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007044309-A2 DEVICE AND METHOD FOR INHIBITING AGE COMPLEX FORMATION VASIX CORPORATION (US) 2007-04-19 WO disclosed