Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903581 | 0.84 | AHR (0.50) | AHRKITMAPTKDM4EALDH1A1 | |
| SCHEMBL10366374 | 0.81 | NPC1 (0.48) | AHRKITMAPTKDM4EALDH1A1 | |
| SCHEMBL5057039 | 0.76 | RAB9A (0.49) | AHRMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL1493316 | 0.75 | KIT (0.46) | AHRKITMAPTKDM4EALDH1A1 | |
| SCHEMBL30512060 | 0.72 | ALKBH5 (0.52) | KITMAPTKDM4ENPC1RXFP1 | |
| SCHEMBL4154898 | 0.71 | MAPT (0.49) | AHRMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL9903796 | 0.70 | KIT (0.43) | KITMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL1490935 | 0.70 | ALKBH5 (0.51) | KITMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31710911 | 0.69 | NPC1 (0.56) | KITMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL30833192 | 0.69 | LMNA (0.36) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039146-A1 | 4-CARBOXY PYRAZOLE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-12 | — | — | WO | disclosed |