Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | CASP3 | P42574 | 2/20 | 1.00 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 1.00 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 1.00 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.83 |
| ▸ | HPGD | P15428 | 3/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310226 | 1.00 | MAPT (1.00) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28774771 | 0.84 | MAPT (0.72) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3040770 | 0.82 | RAB9A (0.69) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3040771 | 0.82 | RAB9A (0.69) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8751517 | 0.80 | EGFR (0.68) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8751516 | 0.80 | EGFR (0.68) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19003260 | 0.80 | RAB9A (0.67) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9767800 | 0.80 | ALDH1A1 (0.67) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19003301 | 0.79 | MAPT (0.65) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18985299 | 0.78 | RAB9A (0.74) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |