Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | CASP3 | P42574 | 3/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003307 | 0.83 | EGFR (0.60) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL19003248 | 0.83 | LMNA (0.56) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL19003301 | 0.82 | MAPT (0.65) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL19003283 | 0.81 | RAB9A (0.52) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL19003257 | 0.80 | KDM4E (0.49) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL5310226 | 0.80 | MAPT (1.00) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL5310230 | 0.80 | MAPT (1.00) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL19003250 | 0.80 | MAPT (0.51) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL19003274 | 0.79 | MMP1 (0.58) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL18985197 | 0.79 | MEN1 (0.55) | RAB9AMAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |