Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 4/20 | 0.55 |
| ▸ | CASP7 | P55210 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956254 | 0.79 | POLB (0.57) | GAAPOLBKMT2AMEN1MAPT | |
| SCHEMBL5310368 | 0.76 | AMY1A (0.71) | GAACASP1CASP7KMT2AMEN1 | |
| SCHEMBL5310365 | 0.76 | AMY1A (0.71) | GAACASP1CASP7KMT2AMEN1 | |
| SCHEMBL6822831 | 0.69 | CASP1 (0.61) | GAAPOLBCASP1CASP7KMT2A | |
| SCHEMBL30640070 | 0.69 | CASP1 (0.61) | GAAPOLBCASP1CASP7KMT2A | |
| SCHEMBL6448832 | 0.69 | CASP1 (0.61) | GAAPOLBCASP1CASP7KMT2A | |
| SCHEMBL6448836 | 0.69 | CASP1 (0.61) | GAAPOLBCASP1CASP7KMT2A | |
| SCHEMBL11343000 | 0.68 | ERN1 (0.68) | GAAPOLBCASP1CASP7KMT2A | |
| SCHEMBL11343002 | 0.68 | ERN1 (0.68) | GAAPOLBCASP1CASP7KMT2A | |
| SCHEMBL9821551 | 0.68 | POLB (0.48) | GAAPOLBMAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |