Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.71 |
| ▸ | CASP1 | P29466 | 4/20 | 0.60 |
| ▸ | CASP7 | P55210 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310365 | 1.00 | AMY1A (0.71) | AMY1ACASP1CASP7GAAALDH1A1 | |
| SCHEMBL3669949 | 0.76 | AMY1A (0.65) | AMY1AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3669947 | 0.76 | AMY1A (0.65) | AMY1AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL5310267 | 0.76 | GAA (0.59) | AMY1ACASP1CASP7GAAALDH1A1 | |
| SCHEMBL6448836 | 0.73 | CASP1 (0.61) | CASP1CASP7GAAALDH1A1MEN1 | |
| SCHEMBL30640070 | 0.73 | CASP1 (0.61) | CASP1CASP7GAAALDH1A1MEN1 | |
| SCHEMBL6822831 | 0.73 | CASP1 (0.61) | CASP1CASP7GAAALDH1A1MEN1 | |
| SCHEMBL6448832 | 0.73 | CASP1 (0.61) | CASP1CASP7GAAALDH1A1MEN1 | |
| SCHEMBL4258545 | 0.72 | CASP1 (0.59) | CASP1CASP7GAAALDH1A1MEN1 | |
| SCHEMBL4346769 | 0.70 | CASP1 (0.62) | CASP1CASP7GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |