Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 9/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423949 | 0.87 | ENPP2 (0.59) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL10574724 | 0.84 | CYP3A4 (0.74) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| Hydrochloric Acid SCHEMBL7658202 | 0.83 | ADH5 (0.51) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| Hydrochloric Acid SCHEMBL7650974 | 0.83 | ADH5 (0.51) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL5303227 | 0.82 | ADH5 (0.52) | ADH5CYP3A4BAZ2BMEN1TSHR | |
| SCHEMBL5303396 | 0.82 | ADH5 (0.52) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL5308132 | 0.81 | ADH5 (0.50) | ADH5CYP3A4BAZ2BMEN1KMT2A | |
| SCHEMBL5309564 | 0.80 | GFER (0.56) | ADH5CYP3A4BAZ2BMEN1ALOX15 | |
| SCHEMBL5313554 | 0.79 | LMNA (0.48) | ADH5CYP3A4BAZ2BMEN1TSHR | |
| SCHEMBL5307796 | 0.79 | ADH5 (0.48) | ADH5CYP3A4BAZ2BHTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039580-A1 | IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | claimed |
| WO-2007039580-A1 | IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |